Upon returning to Nazareth and throwing down incredibly wise teachings on the Kingdom and life (as a tradesmans son) it makes sense that his childhood elders and peers and even family members would be offended at his presumed 'higher education', right?
Then Jesus coins this phrase that's managed to cross cultural and contextual boundaries for centuries now. If only we understood how severely was His rejection here - the Creator of the universe (John 1) was denied trust, faith, respect...honor in his own house by His own creation.
And we still take offense at Him.